| Efficacy of optimal long-term management of multiple cardiovascular risk factors (CVD) on walking and quality of life in patients with peripheral artery disease (PAD): protocol for randomized controlled trial. | |
| | |
MedLine Citation:
|
PMID: 22363015 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Peripheral artery disease (PAD) is an understudied chronic illness most prevalent in elderly individuals. PAD patients experience substantial walking impairment due to symptoms of limb ischemia that significantly diminishes quality of life (QOL). Cardiovascular disease (CVD) morbidity and mortality is increased in this population because of aggressive atherosclerosis resulting from untreated CVD risk factors. Despite current national guidelines recommending intensive CVD risk factor management for PAD patients, untreated CVD risk factors are common. Interventions that bridge this gap are imperative. The Vascular Insufficiency - Goals for Optimal Risk Reduction (VIGOR(2)) study is a randomized controlled trial (RCT) that examines the effectiveness of a long-term multifactor CVD risk reduction program on walking and quality of life in patients with PAD. The purpose of this article is to provide a detailed description of the design and methods of VIGOR(2). Clinical Trial Registration - URL: http://clinicaltrials.gov/ct2/show/NCT00537225. |
| | |
Authors:
|
Roberta K Oka; Michael S Conte; Christopher D Owens; Joseph Rapp; Gordon Fung; Hugh F Alley; John C Giacomini; Jonathan Myers; Emile R Mohler |
Related Documents
:
|
16298255 - Predictors of cardiovascular death in esrd. 22372395 - Temperament, insecure attachment, impulsivity, and sexuality in women in jail. 17030745 - Risk of ischemic complications related to the intensity of triptan and ergotamine use. 22390315 - Attributional style among youth at clinical risk for psychosis. 21569985 - Multivariate relationships among risk factors and hypoesthesia of the lower lip after e... 22707135 - Chlamydia trachomatis serovar distribution and other sexually transmitted coinfections ... |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Vascular medicine (London, England) Volume: 17 ISSN: 1477-0377 ISO Abbreviation: Vasc Med Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-02-24 Completed Date: 2012-06-20 Revised Date: 2013-02-26 |
Medline Journal Info:
|
Nlm Unique ID: 9610930 Medline TA: Vasc Med Country: England |
Other Details:
|
Languages: eng Pagination: 17-28 Citation Subset: IM |
Affiliation:
|
Department of Veteran's Affairs, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA. Roberta.oka@va.gov |
| Data Bank Information | |
Bank Name/Acc. No.:
|
ClinicalTrials.gov/NCT00537225 |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Cardiovascular Diseases / epidemiology* Clinical Protocols* Comorbidity Humans Long-Term Care Middle Aged Peripheral Arterial Disease / epidemiology*, physiopathology, therapy* Quality of Life* Questionnaires Risk Assessment Risk Factors Walking / physiology |
| Grant Support | |
ID/Acronym/Agency:
|
3R01NR009197-04S1/NR/NINR NIH HHS; 3R01NR009197-04S2/NR/NINR NIH HHS; 3R01NR009197-04S3/NR/NINR NIH HHS; 5R01NR9197/NR/NINR NIH HHS; R01 NR009197/NR/NINR NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Progression of asymptomatic peripheral artery disease over 1 year.
Next Document: Test-retest reliability of pulse amplitude tonometry measures of vascular endothelial function: impl...