Document Detail


Efficacy of a nonrestricted fat diet in patients with cystic fibrosis.
MedLine Citation:
PMID:  2929527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We sought to determine if an increased oral intake with a noninvasive nutrition program in patients with cystic fibrosis could influence growth, weight gain, and pulmonary function. Thirty-seven patients, aged 2 to 27 years, were instructed to consume a nonrestricted fat diet during an intervention period of 4 years. The results showed that patients increased the mean energy intake significantly to a level of more than 120% of the recommended daily allowance. The enhanced intake resulted in significant weight gain. Pulmonary function (forced expiratory flow 25%-75%) deteriorated during the 2-year preintervention period but stabilized during the 4-year intervention period. Both male and female patients were able to maintain their established height and weight scores during adolescence. The recommendation for a high-energy diet with no restrictions placed on the fat intake and the control of the steatorrhea by administration of an optimal enzyme dosage is supported by our data. Individualized nutritional counseling should be attempted before implementing invasive nutritional intervention programs.
Authors:
E Luder; M Kattan; J C Thornton; K M Koehler; R J Bonforte
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  143     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-05-02     Completed Date:  1989-05-02     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  458-64     Citation Subset:  AIM; IM    
Affiliation:
Jack and Lucy Clark Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029-6574.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Body Height
Child
Child, Preschool
Cystic Fibrosis / diet therapy*,  physiopathology
Dietary Fats / therapeutic use*
Energy Metabolism
Female
Follow-Up Studies
Humans
Male
Maximal Midexpiratory Flow Rate
Pancreatin / therapeutic use
Prospective Studies
Retrospective Studies
Weight Gain
Grant Support
ID/Acronym/Agency:
MCJ001069//PHS HHS
Chemical
Reg. No./Substance:
0/Dietary Fats; 8049-47-6/Pancreatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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