| Efficacy of a new fractional CO2 laser in the treatment of photodamage and acne scarring. | |
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MedLine Citation:
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PMID: 20666827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study evaluates the efficacy and safety of a novel fractional CO(2) laser device for improving facial rhytids, hyperpigmentation, enlarged pores, skin laxity, and acne scarring. Subjects (n= 15) were treated three to five times at 3-week intervals. Biopsy specimens were used to evaluate healing response and neocollagenesis. Clinical improvement was rated on a quartile rating scale from digital photographs. Subject discomfort during treatment was evaluated on a scale of 0 to 5. Fourteen subjects who completed the study achieved good to excellent improvement in overall appearance, with 60% rated excellent. Improvement in photodamage was good to excellent in 92% of subjects, and reduction in rhytids was good to excellent in 85%. A total of 79% of subjects achieved good to excellent improvement in pore sizes and skin laxity. Subject discomfort during treatment was 3.0 +/- 0.7. Erythema persisted for 2-3 days, and subjects resumed normal activities 1-2 days after the procedure. Histological slides after a single treatment showed new collagen formation. The SmartSkin fractional CO(2) system (Cynosure, Inc., Westford, MA, USA) provides significant improvement for the treatment of facial wrinkles, hyperpigmentation, pore size, and skin laxity associated with photodamage. |
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Authors:
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Bruce Katz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Dermatologic therapy Volume: 23 ISSN: 1529-8019 ISO Abbreviation: Dermatol Ther Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-07-29 Completed Date: 2010-11-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9700070 Medline TA: Dermatol Ther Country: Denmark |
Other Details:
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Languages: eng Pagination: 403-6 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Mt. Sinai School of Medicine, JuvaSkin & Laser Center, New York, New York, USA. brukatz@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
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complications* Adult Aged Aged, 80 and over Cicatrix / etiology, surgery* Collagen / biosynthesis, blood Cosmetic Techniques Face Female Humans Hyperpigmentation / surgery Lasers, Gas / adverse effects, therapeutic use* Middle Aged Patient Satisfaction Skin Aging* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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