| Efficacy of nalidixic acid in the treatment of acute bloody diarrhea. | |
| | |
MedLine Citation:
|
PMID: 2630475 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Of sixty four children (mean age 20.1 +/- 1.2 mo) with acute bloody diarrhea and high fever, 47 had infection with non-typhoidal Salmonella (NTS) (20), Shigella (15) and enteropathogenic E. coli (EPEC) (12) and were treated with nalidixic acid (NA). The mean duration (h) of presence of macroscopic blood in the stool following institution of treatment was significantly shorter (p less than 0.05) in those with EPEC (11.5 +/- 4.9) as compared to NTS (30.4 +/- 15.4) or Shigella groups (22.9 +/- 15.6). The number of children having less than or equal to 50% reduction in stool frequency within 72 h was: NTS (17); Shigella (14); EPEC (10). Negative stool cultures on day 5 were obtained in all patients with Shigella and EPEC and 16 (80%) of those with NTS. Two patients with NTS and one with EPEC failed to respond to NA. |
| | |
Authors:
|
V Khoshoo; P Raj; R Srivastava; N Bhandari; S Sazawal; S Bhatnager; M K Bhan |
Related Documents
:
|
16247515 - Targeting fatty acid synthase: potential for therapeutic intervention in her-2/neu-over... 14663585 - Dormancy termination of western white pine (pinus monticola dougl. ex d. don) seeds is ... 1822685 - Photodegradation of nalidixic and tiaprofenic acids and nifedipine in aerobic conditions. 400825 - Activity of flumequine against escherichia coli: in vitro comparison with nalidixic and... 7364935 - Sex steroid modulation of fatty acid utilization and fatty acid binding protein concent... 16111685 - Estradiol fatty acid esterification is increased in high density lipoprotein subclass 3... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Indian pediatrics Volume: 26 ISSN: 0019-6061 ISO Abbreviation: Indian Pediatr Publication Date: 1989 Nov |
Date Detail:
|
Created Date: 1990-05-10 Completed Date: 1990-05-10 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 2985062R Medline TA: Indian Pediatr Country: INDIA |
Other Details:
|
Languages: eng Pagination: 1135-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Bacterial Infections / drug therapy* Child, Preschool Diarrhea / drug therapy*, etiology Diarrhea, Infantile / drug therapy, etiology Humans Infant Nalidixic Acid / therapeutic use* Occult Blood |
| Chemical | |
Reg. No./Substance:
|
389-08-2/Nalidixic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A community based surveillance system for perinatal and neonatal care.
Next Document: Exchange transfusion in neonatal hyperbilirubinemia.