Document Detail


Efficacy of mineral cationic carrier against sulphur mustard in skin decontamination.
MedLine Citation:
PMID:  19064367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to evaluate decontamination (absorption) efficacy of a preparation called Mineral Cationic Carrier (MCC) against skin contamination with sulphur mustard in vivo. MCC is a synthetic preparation with known ion exchange, absorption efficiency, and bioactive potential. CBA mice were applied increasing doses of sulphur mustard on their skin and MCC was administered immediately after skin contamination. The results have confirmed the decontamination efficacy of MCC preparation, corresponding to 8.4 times the LD50 of percutaneous sulphur mustard, and call for further investigation.
Authors:
Ante Vucemilović; Mirko Hadzija; Ivan Jukić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arhiv za higijenu rada i toksikologiju     Volume:  59     ISSN:  0004-1254     ISO Abbreviation:  Arh Hig Rada Toksikol     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-09     Completed Date:  2009-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373100     Medline TA:  Arh Hig Rada Toksikol     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  289-93     Citation Subset:  IM    
Affiliation:
Institute of Researches and Development of Defense Systems, Zagreb, Croatia. ante.vucemilovic@inet.hr
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MeSH Terms
Descriptor/Qualifier:
Animals
Chemical Warfare Agents / poisoning*
Decontamination*
Lethal Dose 50
Mice
Mice, Inbred CBA
Mustard Gas / poisoning*
Skin / drug effects*
Chemical
Reg. No./Substance:
0/Chemical Warfare Agents; 505-60-2/Mustard Gas

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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