Document Detail

Efficacy of meat and iron-fortified commercial cereal to prevent iron depletion in cow milk-fed infants 6 to 12 months of age: a randomized controlled trial.
MedLine Citation:
PMID:  10986782     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine whether utilization of iron from infant cereal and pureed meat was sufficient to prevent iron depletion and/or anaemia in infants 6 to 12 months old fed whole cow milk (WCM) as their primary milk source.
DESIGN: Six-month-old infants were randomized into a treatment group (n = 43) receiving iron-fortified infant cereal (10.2 mg iron), pureed meat (0.75-1.7 mg iron) and WCM for six months or a control group (n = 54) receiving no dietary intervention. Haemoglobin < 110 g/L or ferritin < 10 micrograms/L (measured bi-monthly), confirmed in a second blood sample, defined end-points.
RESULTS: Proportion reaching end-point was similar between the treatment (3/43) and control infants (5/54) (p = 0.66). Infants not complying with the protocol were at greater risk of reaching end-point (p = 0.0002). Change in haemoglobin and ferritin across age was similar in both groups.
CONCLUSIONS: Iron deficiency is not a concern in WCM-fed infants after six months of age if iron-containing complementary foods are concurrently ingested.
G S Yeung; S H Zlotkin
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of public health = Revue canadienne de santé publique     Volume:  91     ISSN:  0008-4263     ISO Abbreviation:  Can J Public Health     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2000-10-05     Completed Date:  2000-10-05     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  0372714     Medline TA:  Can J Public Health     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  263-7     Citation Subset:  IM    
Department of Nutritional Sciences, University of Toronto, ON.
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MeSH Terms
Anemia, Iron-Deficiency / epidemiology,  prevention & control*
Canada / epidemiology
Food, Fortified / utilization*
Infant Food*
Meat* / utilization

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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