Document Detail


Efficacy of a long-acting oxytetracycline against chlamydial ovine abortion.
MedLine Citation:
PMID:  7337399     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The treatment of ovine abortifacient chlamydias with Terramycin/LA 200 was examined in three successive experiments in which ewes were inoculated intradermally with 6 x 10(5) PFU chlamydia at 80 days of pregnancy. The efficacy of the treatment was estimated by comparing a control group with a treated group for number of live lambs, number of abnormal lambings, length of pregnancy, average weight of lambs at birth and genital excretion of chlamydia at lambing. Sixty to eighty per cent of the ewes in the control group aborted. Under these conditions a single treatment of 20 mg/kg of Terramycin/LA at day 105 of pregnancy, i.e. four weeks after the inoculation, is not effective. On the other hand, a combination of injections, one three weeks and one five weeks after the inoculation, result in longer pregnancies on average, fewer abortions and more liveborn lambs. However, the treatment does not modify either the weight of liveborn lambs or the vaginal excretion of chlamydia at lambing. The adaptation of this treatment to practical conditions and its interest are discussed.
Authors:
A Rodolakis; A Souriau; J P Raynaud; G Brunault
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annales de recherches vétérinaires. Annals of veterinary research     Volume:  11     ISSN:  0003-4193     ISO Abbreviation:  Ann. Rech. Vet.     Publication Date:  1980  
Date Detail:
Created Date:  1982-05-12     Completed Date:  1982-05-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  1267230     Medline TA:  Ann Rech Vet     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  437-44     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abortion, Veterinary / prevention & control*
Animals
Chlamydia Infections / prevention & control*,  veterinary*
Female
Injections, Intramuscular
Oxytetracycline / administration & dosage,  therapeutic use*
Pregnancy
Sheep
Sheep Diseases / prevention & control*
Chemical
Reg. No./Substance:
79-57-2/Oxytetracycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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