| Efficacy in anterior uveitis of two known steroids and topical tolmetin. | |
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MedLine Citation:
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PMID: 3881125 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have compared the anti-inflammatory efficacy of 5% tolmetin sodium dihydrate, 0.5% prednisolone disodium phosphate, and 0.1% betamethasone disodium phosphate in 71 consecutive patients presenting with acute endogenous non-granulomatous uveitis randomly assigned to one of these treatment groups. Inflammatory symptoms and signs were scored during the course of the 21-day trial period. There was no statistically significant difference in the effect on the signs or symptoms of the three drugs tested. 90% of the Betnesol (betamethasone sodium phosphate, benzalkonium chloride) treated group were clinically judged cured compared with 68% of the Predsol (prednisolone sodium phosphate, benzalkonium chloride) treated group, and 57% of the tolmetin treated group. |
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Authors:
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J A Dunne; N Jacobs; A Morrison; D J Gilbert |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The British journal of ophthalmology Volume: 69 ISSN: 0007-1161 ISO Abbreviation: Br J Ophthalmol Publication Date: 1985 Feb |
Date Detail:
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Created Date: 1985-03-19 Completed Date: 1985-03-19 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 120-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Adolescent Adult Aged Anti-Inflammatory Agents / therapeutic use* Betamethasone / analogs & derivatives*, therapeutic use Clinical Trials as Topic Dexamethasone* / analogs & derivatives* Female Humans Intraocular Pressure Male Middle Aged Prednisolone / analogs & derivatives*, therapeutic use Pyrroles / therapeutic use* Tolmetin / therapeutic use* Uveitis / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Pyrroles; 26171-23-3/Tolmetin; 302-25-0/prednisolone phosphate; 312-93-6/dexamethasone 21-phosphate; 378-44-9/Betamethasone; 50-02-2/Dexamethasone; 50-24-8/Prednisolone |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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