Document Detail


Efficacy of ethanolamine and polidocanol in the eradication of esophageal varices. A prospective randomized trial.
MedLine Citation:
PMID:  2693076     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective randomized trial has been undertaken to compare the efficacy of two sclerosing agents, Ethanolamine oleate (Et) and Polidocanol (Pl), in the eradication of esophageal varices (EV). Fifty consecutive cirrhotic patients, 22 in the Et and 28 in the Pl group, were included. Clinical data were comparable in both groups. Eradication of the EV was achieved in 81% (18/22) in the Et group and 64.1% (18/28) in the Pl group (p = NS). There was a significant difference in the rate of rebleeding (4 episodes in 3 patients in the Et group and 18 episodes in 13 patients in the Pl group, p less than 0.05). No differences were noted in the number of other complications or mortality. Both sclerosants have proved useful in the eradication of EV, but Et was superior to Pl in the preventation of recurrent bleeding in the course of repeated endoscopic injection sclerotherapy (EIS).
Authors:
J Balanzó; S Sainz; J C Espinós; J Such; J Segura; C Guarner; X Cussó; F Vilardell
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Endoscopy     Volume:  21     ISSN:  0013-726X     ISO Abbreviation:  Endoscopy     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-03-08     Completed Date:  1990-03-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0215166     Medline TA:  Endoscopy     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  251-3     Citation Subset:  IM    
Affiliation:
Escuela de Patología Digestiva, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
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MeSH Terms
Descriptor/Qualifier:
Esophageal and Gastric Varices / therapy*
Female
Humans
Male
Middle Aged
Oleic Acids / therapeutic use*
Polyethylene Glycols / therapeutic use*
Prospective Studies
Randomized Controlled Trials as Topic
Sclerosing Solutions / therapeutic use*
Chemical
Reg. No./Substance:
0/Oleic Acids; 0/Polyethylene Glycols; 0/Sclerosing Solutions; 3282-75-5/ethanolamine oleate; 9002-92-0/polidocanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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