| Efficacy of duloxetine for the treatment of depression: relationship to most recent antidepressant trial. | |
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MedLine Citation:
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PMID: 18362869 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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To describe and examine, in a sample of depressed outpatients, the relationship between level of response to a previous SSRI or SNRI antidepressant trial and subsequent response to duloxetine hydrochloride. Data collected from a multicenter trial that evaluated the safety and efficacy of duloxetine for the treatment of major depressive disorder were analyzed to determine the relationship between response to previous antidepressant treatment and degree of response to duloxetine. Time to first response, first remission, sustained response, and sustained remission during the first 12 weeks of duloxetine treatment were compared across patient groups. Principal Observations: Response and remission with duloxetine treatment ranged between 57 and 68% and 29 and 57%, respectively, and did not differ significantly across previous response levels. |
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Authors:
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Timothy Petersen; Roy H Perlis; Chris Ticknor; Jim Lohr; H Brent Solvason; John P O'Reardon; Madelaine M Wohlreich; Charissa Andreotti; Michael Wilson; Maurizio Fava |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Psychopharmacology bulletin Volume: 41 ISSN: 0048-5764 ISO Abbreviation: Psychopharmacol Bull Publication Date: 2008 |
Date Detail:
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Created Date: 2008-03-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0101123 Medline TA: Psychopharmacol Bull Country: United States |
Other Details:
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Languages: eng Pagination: 34-45 Citation Subset: IM |
Affiliation:
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Division of Postgraduate Education, Department of Psychiatry, Massachusetts General Hospital, Boston, MA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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