Document Detail

Efficacy of dual-source CT coronary angiography in evaluating coronary stenosis: initial experience.
MedLine Citation:
PMID:  20416479     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To retrospectively assess the diagnostic efficacy of dual-source CT angiography (DSCTA) in detecting and grading coronary stenosis. METHODS: Institutional review board approval and informed consent were obtained. One hundred ten patients were performed with both DSCTA and conventional coronary angiography (CCA) without heart rate or rhythm control in 1 week. Regarding CCA as the gold standard, the assessable rate of coronary arteries and diagnostic value of coronary stenosis using DSCTA were analyzed, respectively. The intermodality agreement between DSCTA and CCA in grading coronary stenosis was assessed using kappa test. The value of DSCTA in diagnosing >50% coronary stenoses was also assessed. RESULTS: The overall assessable rate of DSCTA was 98.6% in detecting coronary arteries; there was no significant difference between assessable rates from different groups of heart rate (chi(2)=0.45, P > .05). The efficacy of DSCTA was of 97.9% sensitivity, 97.3% specificity, 90.4% positive predictive value, and 99.4% negative predictive value for coronary stenosis; and 94.7% sensitivity, 96.8% specificity, 83.7% positive predictive value, and 99% negative predictive value for >50% stenoses. The intermodality agreement in diagnosing coronary stenosis was satisfactory (k=0.87, u=58.46, P<.01). CONCLUSIONS: As an effective noninvasive diagnostic tool, DSCTA yields a promising accuracy and reliability in assessing coronary stenosis. It may be recommended as a valuable screening tool for coronary artery disease, and a potential challenge to CCA as well.
Hong-wei Chen; Xiang-ming Fang; Xiao-yun Hu; Jian Bao; Chun-hong Hu; Yin Chen; Zhen-yu Yang; Lerner Alexander; Xiao-qing Wu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical imaging     Volume:  34     ISSN:  1873-4499     ISO Abbreviation:  Clin Imaging     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-07-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911831     Medline TA:  Clin Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  165-71     Citation Subset:  IM    
Imaging Center, Wuxi People's Hospital, Nanjing Medical University, 214023, Wuxi City, Jiangsu Province, People's Republic of China.
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MeSH Terms
Aged, 80 and over
Coronary Angiography / methods*
Coronary Stenosis / radiography*
Middle Aged
Pilot Projects
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*

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