| Efficacy of double arterial phase dynamic magnetic resonance imaging with the sensitivity encoding technique versus dynamic multidetector-row helical computed tomography for detecting hypervascular hepatocellular carcinoma. | |
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MedLine Citation:
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PMID: 19626408 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The aim of this study was to evaluate the efficacy of double arterial phase dynamic magnetic resonance imaging (MRI) with the sensitivity encoding technique (SENSE dynamic MRI) for detection of hypervascular hepatocellular carcinoma (HCC) in comparison with double arterial phase dynamic multidetector-row helical computed tomography (dynamic MDCT). MATERIALS AND METHODS: A total of 28 patients with 66 hypervascular HCCs underwent both double arterial SENSE dynamic MRI and dynamic MDCT. The diagnosis of HCC was based on surgical resection (n = 7), biopsy (n = 10), or a combination of CT during arterial portography (CTAP), CT during hepatic arteriography (CTA), and/or the 6-month follow-up CT (n = 49). Based on alternative-free response receiving operating characteristic (ROC) analysis, the diagnostic performance for detecting HCC was compared between double arterial phase SENSE dynamic MRI and double arterial phase dynamic MDCT. RESULTS: The mean sensitivity, positive predictive value, and mean Az values for hypervascular HCCs were 72%, 80%, and 0.79, respectively, for SENSE dynamic MRI and 66%, 92%, and 0.78, respectively, for dynamic MDCT. The mean sensitivity for double arterial phase SENSE dynamic MRI was higher than that for double arterial phase dynamic MDCT, but the difference was not statistically significant. CONCLUSION: Double arterial phase SENSE dynamic MRI is as valuable as double arterial phase dynamic MDCT for detecting hypervascular HCCs. |
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Authors:
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Seishi Kumano; Masahiko Uemura; Toyoaki Haraikawa; Masaaki Hirata; Keiichi Kikuchi; Tonsok Kim; Masahiro Okada; Teruhito Mochizuki; Takamichi Murakami |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2009-07-22 |
Journal Detail:
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Title: Japanese journal of radiology Volume: 27 ISSN: 1867-1071 ISO Abbreviation: Jpn J Radiol Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-07-23 Completed Date: 2009-10-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101490689 Medline TA: Jpn J Radiol Country: Japan |
Other Details:
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Languages: eng Pagination: 229-36 Citation Subset: IM |
Affiliation:
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Department of Radiology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osakasayama 589-8511, Japan. kumano@radiol.med.kindai.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Carcinoma, Hepatocellular / pathology*, radiography* Contrast Media / diagnostic use Diagnosis, Differential Female Follow-Up Studies Gadolinium DTPA / diagnostic use Humans Image Enhancement / methods Imaging, Three-Dimensional / methods Liver / pathology, radiography Liver Neoplasms / pathology*, radiography* Magnetic Resonance Imaging / methods* Male Middle Aged Observer Variation ROC Curve Retrospective Studies Sensitivity and Specificity Tomography, Spiral Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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