Document Detail

Efficacy of donkey's milk in treating highly problematic cow's milk allergic children: an in vivo and in vitro study.
MedLine Citation:
PMID:  17433003     Owner:  NLM     Status:  MEDLINE    
Successful therapy in cow's milk protein allergy rests on completely eliminating cow's milk proteins from the child's diet: it is thus necessary to provide a replacement food. This prospective study investigated tolerance of donkey's milk in a population of 46 selected children with cow's milk protein allergy, for whom it was not possible to use any cow's milk substitute. Thirty-eight children (82.6%) liked and tolerated donkey's milk at the challenge and for the entire duration of follow-up. Catch-up growth was observed in all subjects with growth deficit during cow's milk proteins challenge. The degree of cross-reactivity of immunoglobulin E (IgE) with donkey's milk proteins was very weak and aspecific. Donkey's milk was found to be a valid alternative to both IgE-mediated and non-IgE-mediated cow's milk proteins allergy, including in terms of palatability and weight-height gain.
Giovanna Monti; Enrico Bertino; Maria Cristina Muratore; Alessandra Coscia; Francesco Cresi; Leandra Silvestro; Claudio Fabris; Donatella Fortunato; Maria Gabriella Giuffrida; Amedeo Conti
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology     Volume:  18     ISSN:  0905-6157     ISO Abbreviation:  Pediatr Allergy Immunol     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-16     Completed Date:  2007-06-26     Revised Date:  2008-05-28    
Medline Journal Info:
Nlm Unique ID:  9106718     Medline TA:  Pediatr Allergy Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  258-64     Citation Subset:  IM    
Department of Paediatric and Adolescence Science, Regina Margherita Children's Hospital, Turin, Italy.
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MeSH Terms
Child, Preschool
Milk* / adverse effects
Milk Hypersensitivity / diet therapy*,  etiology
Prospective Studies
Treatment Outcome
Comment In:
Pediatr Allergy Immunol. 2007 Nov;18(7):625-6   [PMID:  18001434 ]

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