Document Detail


Efficacy of dietary treatments for epilepsy.
MedLine Citation:
PMID:  20487176     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ketogenic diet (KD) is a high fat, restricted carbohydrate regime that has been used as a treatment for seizures since the 1920s, when it was designed to induce a similar metabolic response to fasting. A modification of this early classical version of the KD was introduced in the 1970s using medium chain triglycerides as an alternative fat source. More recently, two alternative, less-restrictive dietary treatments have been developed: the modified Atkins diet and the low glycaemic index diet. There are many case reports and observational studies reporting successful use of the KD, and a growing number of studies reporting similar success with the modified Atkins protocol. A recent randomised controlled trial has shown a significant benefit of the KD compared to no change in treatment. The use of these dietary therapies in the UK is supported by literature evidence, although often is limited by a lack of resources; increasing awareness and knowledge is fundamental to ensure availability for those individuals with intractable epilepsy who may benefit from them.
Authors:
E G Neal; J H Cross
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of human nutrition and dietetics : the official journal of the British Dietetic Association     Volume:  23     ISSN:  1365-277X     ISO Abbreviation:  J Hum Nutr Diet     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-05-21     Completed Date:  2010-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8904840     Medline TA:  J Hum Nutr Diet     Country:  England    
Other Details:
Languages:  eng     Pagination:  113-9     Citation Subset:  IM    
Affiliation:
Neurosciences Unit, Institute of Child Health, London, UK. l.neal@ich.ucl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Diet, Carbohydrate-Restricted*
Epilepsy / diet therapy*
Glycemic Index
Humans
Ketogenic Diet*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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