| Efficacy of desensitizing dentifrices to occlude dentinal tubules. | |
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MedLine Citation:
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PMID: 22112037 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy of desensitizing dentifrices to occlude dentinal tubules. Eur J Oral Sci 2011; 119: 497-503. © 2011 Eur J Oral Sci Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine-containing dentifrice, two established strontium-based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate- and arginine-containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity. |
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Authors:
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Maria Davies; Elizabeth M Paice; Sian B Jones; Sam Leary; Andrew R Curtis; Nicola X West |
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Publication Detail:
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Type: Journal Article Date: 2011-10-11 |
Journal Detail:
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Title: European journal of oral sciences Volume: 119 ISSN: 1600-0722 ISO Abbreviation: Eur. J. Oral Sci. Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9504563 Medline TA: Eur J Oral Sci Country: Denmark |
Other Details:
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Languages: eng Pagination: 497-503 Citation Subset: D; IM |
Copyright Information:
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© 2011 Eur J Oral Sci. |
Affiliation:
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Clinical Trials Group, School of Oral and Dental Science, University of Bristol, Bristol School of Oral and Dental Science, University of Bristol, Bristol, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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