Document Detail


Efficacy of desensitization via the sublingual route in mite allergy.
MedLine Citation:
PMID:  12947993     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Desensitization via the sublingual route when treating mite allergy is a new technique in immunotherapy that has aroused the interest of an increasing number of allergists. Assessing its effectiveness is difficult because of the multiplicity of the criteria used by the various published studies to determine what constitutes an improvement. But a critical analysis of the results obtained in the various methodologically rigorous studies suggests that treatment is effective when compared to a placebo. It remains, however, necessary to determine whether or not the sublingual route is superior to the subcutaneous route; its ease of use and harmlessness should not be the only criteria when deciding upon a treatment that above all else should be curative.
Authors:
Stéphane Guez
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Chemical immunology and allergy     Volume:  82     ISSN:  1660-2242     ISO Abbreviation:  Chem Immunol Allergy     Publication Date:  2003  
Date Detail:
Created Date:  2003-09-01     Completed Date:  2003-10-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101183835     Medline TA:  Chem Immunol Allergy     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  62-76     Citation Subset:  IM    
Affiliation:
Unité des Maladies Allergiques, Hôpital Pellegrin-Tripode, Bordeaux, France. stephane.guez@chu-bordeaux.fr
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MeSH Terms
Descriptor/Qualifier:
Administration, Sublingual
Allergens / administration & dosage*
Animals
Clinical Trials as Topic
Desensitization, Immunologic / methods*
Humans
Hypersensitivity / therapy*
Mites / immunology*
Chemical
Reg. No./Substance:
0/Allergens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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