| Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin. | |
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MedLine Citation:
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PMID: 22236139 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The present study aimed to evaluate the photoprotective effects of cosmetic formulations containing a dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin, as well as their effects on the hydration and viscoelastic skin properties. The photoprotection was determined in vitro (antioxidant activity) and in vivo on UV-irradiated hairless mouse skin. The hydration effects were performed with the application of the formulations under study on the forearm of human volunteers and skin conditions were analysed before and after a single application and daily applications during 4 weeks in terms of transepidermal water loss (TEWL), skin moisture and viscoelastic properties. The raw material under study possessed free-radical scavenging activity and the formulation with it protected hairless mouse skin barrier function against UV damage. After 4-weeks of application on human skin, the formulation under study enhanced stratum corneum skin moisture and also showed hydration effect in deeper layers of the skin. Thus, it can be concluded that the cosmetic formulation containing a dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin under study showed photoprotective effects in skin barrier function as well as pronounced hydration effects on human skin, which suggests that this dispersion has potential anti-ageing effects. © 2012 Wiley Periodicals, Inc. Photochemistry and Photobiology© 2012 The American Society of Photobiology. |
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Authors:
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Patrícia Maria Berardo Gonçalves Maia Campos; Flávio Bueno de Camargo; Jirrah Pedro de Andrade; Lorena Rigo Gaspar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-12 |
Journal Detail:
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Title: Photochemistry and photobiology Volume: - ISSN: 1751-1097 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376425 Medline TA: Photochem Photobiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 Wiley Periodicals, Inc. Photochemistry and Photobiology © 2012 The American Society of Photobiology. |
Affiliation:
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Departamento de Ciências Farmacêuticas da Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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