| Efficacy of cone biopsy of the uterine cervix during frozen section for the evaluation of cervical intraepithelial neoplasia grade 3. | |
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MedLine Citation:
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PMID: 15362368 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We retrospectively selected 22 cases in which patients with a biopsy-proven diagnosis of cervical intraepithelial neoplasia grade 3 underwent cervical conization for frozen section (FS) evaluation followed by hysterectomy at the University of California Irvine Medical Center, Orange, during the August 1995 to September 9, 2001. All slides from FS and permanent section (PS) and hysterectomy specimens were reviewed. FS diagnoses were compared with those of previous biopsies, PS, and hysterectomy specimens. The PS correlated with FS in all cases but 1. Appropriate surgery was performed for all patients based on FS diagnosis. The McNemar test was used to compare the results of FS and PS, with a 2-sided P value of 1.0 and a c coefficient of 0.7755 with a 95% confidence level, indicating that the 2 groups were not significantly different. FS evaluation of cervical conization is as efficacious and accurate as evaluation of regular specimens in providing information for the appropriateness of same-day surgery. We recommend that entire tissue be submitted for FS to avoid sampling errors and to increase diagnostic accuracy. |
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Authors:
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Mai Gu; Fritz Lin |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of clinical pathology Volume: 122 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-09-14 Completed Date: 2004-10-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 383-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Pathology, University of California Irvine Medical Center, Orange 92868, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cervical Intraepithelial Neoplasia / pathology* Conization* Female Frozen Sections Humans Middle Aged Reproducibility of Results Retrospective Studies Sensitivity and Specificity Uterine Cervical Neoplasms / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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