| [Efficacy of compound xuanju capsule combined with bromocriptine on hyperprolactinemia-induced erectile dysfunction]. | |
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MedLine Citation:
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PMID: 23214255 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the effect of Compound Xuanju Capsule (CXC) combined with bromocriptine on hyperprolactinemia-induced erectile dysfunction (ED). METHODS: We randomly assigned 46 patients with hyperprolactinemia-induced ED to receive bromocriptine (trial group, n = 23) and bromocriptine plus CXC (control group, n = 23), respectively, both for 12 weeks. Then we compared the two groups of patients in erectile function and the levels of serum prolactin and testosterone. RESULTS: After 12 weeks of treatment, the IIEF-5 scores were significantly improved in both the trial and the control groups as compared with the baseline (19.5 +/- 4.1 vs 13.0 +/- 3.8 and 16.4 +/- 3.7 vs 13.7 +/- 3.5, P<0.05), the level of serum prolactin was remarkably decreased ([156.07 +/- 26.31] vs [478.35 +/- 62.28] mIU/L and [164.73 +/- 28.58] vs [445.26 +/- 57.83] mIU/L, P<0.05), while the level of serum testosterone was markedly increased ([15.34 +/- 5.27] vs [3.80 +/- 1.09] nmol/L and [12.02 +/- 2.36] vs [4.07 +/- 1.25] nmol/L, P<0.05). Post-treatment erectile function was significantly better in the trial than in the control group (P<0.05), and the post-treatment serum testosterone level remarkably higher in the former than in the latter (P<0.05), but there was no significant difference in the serum prolactin level after treatment between the two groups (P>0.05). CONCLUSION: The combination of Compound Xuanju Capsule and bromocriptine is highly effective in the treatment of hyperprolactinemia-induced ED, and its effect is even better than that of bromocriptine alone. |
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Authors:
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Jun Bian; Cun-Dong Liu; Xiang-Zhou Sun; Chun-Hua Deng; Yan-Ping Huang; Yun-Lin Ye |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Zhonghua nan ke xue = National journal of andrology Volume: 18 ISSN: 1009-3591 ISO Abbreviation: Zhonghua Nan Ke Xue Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-12-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101093592 Medline TA: Zhonghua Nan Ke Xue Country: China |
Other Details:
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Languages: chi Pagination: 1023-7 Citation Subset: IM |
Affiliation:
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Department of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong 510630, China. bianjun39@163.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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