Document Detail

Efficacy and complications of argon plasma coagulation for hematochezia related to radiation proctopathy.
MedLine Citation:
PMID:  11756918     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Endoscopic treatments effectively control bleeding caused by radiation proctopathy. The aims of this study were to determine the efficacy and side effects of argon plasma coagulation in the treatment of this type of bleeding. METHODS: Records of 21 consecutive patients in whom argon plasma coagulation was used to treat hemorrhagic radiation proctopathy were reviewed. RESULTS: Pharmacologic measures had been unsuccessful in 12 patients. Endoscopic treatment had been unsuccessful in 5 patients. All patients were anemic and 4 had received blood transfusions. The mean number of treatment sessions was 1.7, and 10 patients were successfully treated in single session. Rectal bleeding resolved within 1 month of the last treatment in 19 patients, usually on the day of the last procedure. Bleeding resolved 2 months after cessation of therapy in another patient. Short-term side effects occurred in 3 (14%) patients (rectal pain, tenesmus, and/or abdominal distention); long-term complications (rectal pain, tenesmus, diarrhea) developed in 4 patients (19%). CONCLUSIONS: Hematochezia caused by radiation proctopathy is effectively controlled by argon plasma coagulation, in some cases after a single treatment session. Treatment may result in protracted bowel symptoms.
Raphael T Villavicencio; Douglas K Rex; Emad Rahmani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gastrointestinal endoscopy     Volume:  55     ISSN:  0016-5107     ISO Abbreviation:  Gastrointest. Endosc.     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2001-12-28     Completed Date:  2002-01-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0010505     Medline TA:  Gastrointest Endosc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  70-4     Citation Subset:  IM    
Department of Medicine and Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
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MeSH Terms
Aged, 80 and over
Endoscopy, Gastrointestinal
Gastrointestinal Hemorrhage / etiology,  surgery*
Hemostasis, Endoscopic* / adverse effects
Laser Coagulation* / adverse effects
Middle Aged
Radiation Injuries / pathology,  surgery*
Rectal Diseases / etiology,  pathology,  surgery*
Comment In:
Gastrointest Endosc. 2002 Nov;56(5):779-81   [PMID:  12437014 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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