Document Detail

Efficacy of antibiotic-impregnated external ventricular drain catheters.
MedLine Citation:
PMID:  20074964     Owner:  NLM     Status:  MEDLINE    
We prospectively compared the incidence of ventriculitis associated with external ventricular drains (EVD) impregnated with clindamycin and rifampicin with historical controls. We found the use of antibiotic impregnated (AI) EVDs showed a significant decrease in positive cerebrospinal fluid cultures and a significant delay in time to EVD infection.
S Muttaiyah; S Ritchie; S John; E Mee; S Roberts
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Publication Detail:
Type:  Journal Article     Date:  2010-01-13
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  17     ISSN:  1532-2653     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-15     Completed Date:  2010-04-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  296-8     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ltd. All rights reserved.
Department of Microbiology, Auckland City Hospital, Private Bag 92024, Grafton, Auckland 1023, New Zealand.
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MeSH Terms
Aged, 80 and over
Anti-Infective Agents, Local / administration & dosage*
Antibiotic Prophylaxis*
Catheters, Indwelling / adverse effects*,  microbiology
Central Nervous System Infections / cerebrospinal fluid,  etiology,  surgery
Cerebrospinal Fluid Shunts / adverse effects*,  methods
Child, Preschool
Clindamycin / administration & dosage
Infant, Newborn
Intracranial Hypertension / etiology,  prevention & control
Middle Aged
Prospective Studies
Rifampin / administration & dosage
Young Adult
Reg. No./Substance:
0/Anti-Infective Agents, Local; 13292-46-1/Rifampin; 18323-44-9/Clindamycin

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