| Efficacy of adalimumab therapy for life-threatening pulmonary vasculitis in Behçet's disease. | |
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MedLine Citation:
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PMID: 23412691 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Inflammatory large-vessel vasculitis in Behçet's disease may cause life-threatening arterial aneurysms that are prone to rupture. We report a patient with Behçet's disease with right ventricular thrombus and large aneurysms of the pulmonary arteries that led to recurrent episodes of hemoptysis. Following relapses and only partial response to repeated courses of cyclophosphamide and steroids, the patient was treated with adalimumab (Humira) and is now in clinical remission for over 30 months, with regression of her pulmonary lesions. Anti-TNFα treatment is a potential therapeutic option in patients with life-threatening complications due to large-vessel vasculitis. |
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Authors:
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Suhail Aamar; Hagit Peleg; David Leibowitz; Tova Chajek-Shaul; Nurith Hiller; Samuel N Heyman |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-2-15 |
Journal Detail:
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Title: Rheumatology international Volume: - ISSN: 1437-160X ISO Abbreviation: Rheumatol. Int. Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-2-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8206885 Medline TA: Rheumatol Int Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Medicine, Hadassah Hebrew University Hospital, Mt. Scopus, P.O. Box 24035, 91240, Jerusalem, Israel. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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