| Efficacy of pharmacopuncture using root bark of Ulmus davidiana Planch in patients with knee osteoarthritis: a double-blind randomized controlled trial. | |
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MedLine Citation:
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PMID: 20633511 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to determine whether pharmacopuncture is a clinically effective and safe method for the treatment of knee osteoarthritis. Patients were recruited between August 2008 and December 2008 at the Ilsan Hospital associated with Dongguk University. Patients were randomly assigned to one of the two groups. The experimental group (n = 30) received pharmacopuncture using root bark of Ulmus davidiana Planch (UDP) twice a week for 6 weeks; the control group (n = 30) received normal saline injections. Fifty-three patients completed the trial. After the seventh treatment, we found that UDP pharmacopuncture was more effective in pain improvement using a Visual Analog Scale than was normal saline injection. However, the two interventions were not significantly different as measured by the Western Ontario and McMaster Universities pain score and total pain scores, 36-Item Short Form Health Survey, and Korean Health Assessment Questionnaire. No subject showed any serious adverse effects. The effects of pharmacopuncture treatment were a combination of placebo, needle stimulation, mechanical effect of the solution, and a chemical effect of UDP. However, normal saline used as the control intervention displayed the first three effects, and thus its effect was not inert. This may have influenced the results of the trial, which was statistically insignificant between the two groups, except following the seventh treatment session. |
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Authors:
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Eun-Jung Kim; Min-Ki Jang; Eun-Hye Yoon; Chan-Yung Jung; Dong-Woo Nam; Seung-Deok Lee; Kap-Sung Kim |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of acupuncture and meridian studies Volume: 3 ISSN: 2005-2901 ISO Abbreviation: J Acupunct Meridian Stud Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-07-16 Completed Date: 2010-10-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101490763 Medline TA: J Acupunct Meridian Stud Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 16-23 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 Korean Pharmacopuncture Institute. Published by .. All rights reserved. |
Affiliation:
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Department of Acupuncture and Moxibustion, Graduate School of Oriental Medicine, Dongguk University in Seoul, Goyang, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Double-Blind Method Drug Administration Schedule Female Humans Injections, Subcutaneous Male Middle Aged Osteoarthritis, Knee / drug therapy* Plant Bark / chemistry Plant Extracts / administration & dosage* Treatment Outcome Ulmus / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Plant Extracts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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