Document Detail

The Efficacy of a Novel Approach to Transversus Abdominis Plane Block for Postoperative Analgesia After Colorectal Surgery.
MedLine Citation:
PMID:  21467560     Owner:  NLM     Status:  Publisher    
Background: The analgesic efficacy of transversus abdominis plane (TAP) block has been established for patients undergoing abdominal surgery. We evaluated the efficacy of a novel approach to TAP block for postoperative analgesia after colorectal surgery. Methods: Forty adult ASA physical status I to III patients undergoing colorectal surgery were recruited to this double-blind randomized controlled trial. A standard general anesthetic technique was used. TAP block was performed at the end of surgery by piercing the transversus abdominis muscle from inside the abdominal wall at the midaxillary line at the level of the umbilicus with a 22-gauge blunt needle. The patients were randomly assigned to receive either 20 mL of 0.25% bupivacaine (TAP group) or normal saline (control group) on each side of the abdominal wall. Each patient was assessed at 0, 0.5, 1, 2, 4, 8, 12, and 24 hours postoperatively for pain at rest and on coughing using a visual analog scale. IV morphine was used for postoperative rescue analgesia. Time to first request for rescue analgesia, total morphine requirement in 24 hours, cumulative morphine consumption at 2, 4, 6, 12, and 24 hours, and adverse effects (respiratory depression, sedation, nausea/vomiting) were recorded. Results: A 65% decrease in 24-hour total morphine consumption was observed in the TAP group compared with the control group (P < 0.0001). The cumulative morphine requirement was also significantly lower in the TAP group at all time points. Although the time to first request for morphine was comparable, the subsequent doses of morphine were required at significantly longer time intervals in the TAP group than in the control group. TAP group patients had significantly lower pain scores at rest and on coughing as compared with the control group, at all time points assessed. The incidence of sedation was also less in the TAP group at 1, 2, 4, and 6 hours postoperatively (P < 0.05). Conclusions: This new approach to the TAP block provides effective postoperative analgesia after colorectal surgery.
Neerja Bharti; Parag Kumar; Indu Bala; Vikas Gupta
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-5
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  -     ISSN:  1526-7598     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
From the Departments of *Anesthesia and Intensive Care, and.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Positioning an Intra-Aortic Balloon Pump Using Intraoperative Transesophageal Echocardiogram Guidanc...
Next Document:  Missed Steps in the Preanesthetic Set-Up.