Document Detail

Efficacy of Nyoshinsan/TJ-67, a traditional herbal medicine, for menopausal symtoms following surgery and adjuvant chemotherapy for premenopausal breast cancer.
MedLine Citation:
PMID:  18463968     Owner:  NLM     Status:  MEDLINE    
We report a 39-year-old woman with premenopausal breast cancer who developed estrogen-deficiency symptoms associated with chemotherapy-related amenorrhea, and was successfully treated with Nyoshinsan/TJ-67, a Japanese traditional herbal medicine (Kampo). Six other breast cancer survivors with menopausal symptoms were also treated with Nyoshinsan/TJ-67, and five of the six patients showed noticeable improvement without adverse effects. Managing estrogen-deficiency symptoms in breast cancer survivors is still problematic, and Nyoshinsan/TJ-67 may be a useful and safe agent for such symptoms in these patients.
Toshiaki Kogure; Katsuhiko Ito; Hiroko Sato; Tomoyuki Ito; Yuko Oku; Jun Horiguchi; Izumi Takeyoshi; Takeshi Tatsumi
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-05-08
Journal Detail:
Title:  International journal of clinical oncology     Volume:  13     ISSN:  1341-9625     ISO Abbreviation:  Int. J. Clin. Oncol.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-05-08     Completed Date:  2008-10-22     Revised Date:  2012-12-13    
Medline Journal Info:
Nlm Unique ID:  9616295     Medline TA:  Int J Clin Oncol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  185-9     Citation Subset:  IM    
Department of Integrated Japanese Oriental Medicine, School of Medicine, Gunma University, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
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MeSH Terms
Antineoplastic Agents / adverse effects*
Breast Neoplasms / drug therapy*
Chemotherapy, Adjuvant / adverse effects
Estrogens / deficiency*
Herbal Medicine
Middle Aged
Plant Extracts / therapeutic use*
Reg. No./Substance:
0/Antineoplastic Agents; 0/Estrogens; 0/Plant Extracts; 0/nyoshinsan

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