Document Detail

Efficacy of 5% imiquimod cream in a patient with classic Kaposi sarcoma.
MedLine Citation:
PMID:  22826720     Owner:  NLM     Status:  PubMed-not-MEDLINE    
BACKGROUND: The classic Kaposi sarcoma is most common in the Mediterranean population over 50 years of age and presents with reddish-brown papules and nodules particularly on the lower limbs. Treatment depends on the clinical presentation and extension of lesions. Imiquimod is as an immune response modifier with antiangiogenic activity.
MAIN OBSERVATIONS: We present a 74-year-old man with classic Kaposi sarcoma who had multiple, small, violaceous papules and nodules on the trunk and extremities with a history of 14 years. He complained particularly from plantar hyperkeratotic painful nodules. Treatment with imiquimod 5% cream under occlusion resulted with almost complete regression within 12 weeks. No local or systemic side effects were observed.
CONCLUSIONS: Topical imiquimod was a safe and effective therapy in our patient with classic Kaposi sarcoma.
Kamer Gündüz; Umran Günay; Işıl Inanir; Gülsüm Gençoğlan; Peyker Temiz
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of dermatological case reports     Volume:  6     ISSN:  1898-7249     ISO Abbreviation:  J Dermatol Case Rep     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-07-24     Completed Date:  2012-10-02     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101493700     Medline TA:  J Dermatol Case Rep     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  52-3     Citation Subset:  -    
Department of Dermatology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
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