| Efficacy of 308-nm excimer light for Japanese patients with psoriasis. | |
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MedLine Citation:
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PMID: 19878389 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ultraviolet irradiation therapy, including psoralen and ultraviolet A therapy and narrow-band ultraviolet B (310-312 nm) therapy, is a widely used and highly efficient treatment modality for psoriasis. Therapy with 308-nm excimer light has been reported to be effective for the treatment of psoriasis vulgaris. To evaluate the efficacy of 308-nm excimer light therapy for Japanese psoriasis patients, seven patients (six men and one woman) with plaque-type psoriasis were treated with 308-nm excimer light at 7-14-day intervals. The Psoriasis Severity Index (PSI) was calculated for individual plaques in order to assess the effectiveness of the therapy. A 74.9% mean improvement in the PSI was observed after 10 treatment sessions. These results suggested that targeted irradiation with 308-nm excimer light leads to rapid and selective improvement in plaque-type psoriatic lesions without unnecessary radiation exposure to the surrounding unaffected skin. |
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Authors:
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Yusuke Niwa; Toshio Hasegawa; Subin Ko; Yasuhiro Okuyama; Akiko Ohtsuki; Atsushi Takagi; Shigaku Ikeda |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of dermatology Volume: 36 ISSN: 1346-8138 ISO Abbreviation: J. Dermatol. Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-11-02 Completed Date: 2010-01-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 579-82 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan. niwa-yu@juntendo.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Dose-Response Relationship, Radiation Female Follow-Up Studies Humans Japan Male Middle Aged Psoriasis / diagnosis, radiotherapy* Quality of Life Radiotherapy Dosage Sampling Studies Severity of Illness Index Skin / radiation effects* Treatment Outcome Ultraviolet Rays Ultraviolet Therapy / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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