Document Detail


[Effects of yijing recipe on sperm apoptosis and mitochondrial membrane potential in patients with idiopathic oligoathenoteratospermia].
MedLine Citation:
PMID:  23214258     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To investigate the effects of Yijing Recipe on sperm apoptosis and mitochondrial membrane potential (MMP) in patients with idiopathic oligoathenoteratospermia.
METHODS: Using the self-control method, we examined sperm apoptosis and MMP in 30 patients with oligoathenoteratospermia before and after treated with Yijing Recipe.
RESULTS: The rates of early sperm apoptosis (AV +/PI -) and MMP loss were significantly reduced after treatment as compared with pre-medication ([2.86 +/- 1.47]% vs [4.26 +/- 2.79]% and [21.77 +/- 13.46]% vs [41.73 +/- 20.30]%, P<0.05). No statistically significant difference was observed in the sperm death rate (PI+) before and after treatment ([34.10 +/- 16.26]% vs [30.21 +/- 13.50]%, P>0.05).
CONCLUSION: Yijing Recipe can reduce early sperm apoptosis and improve MMP, which may be one of the mechanisms underlying its efficacy on oligoathenoteratospermia.
Authors:
Yong-Zheng Jiao; Ling-Dong Meng; Wei-Guo Ma; Jin-Ming Jia
Publication Detail:
Type:  English Abstract; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Zhonghua nan ke xue = National journal of andrology     Volume:  18     ISSN:  1009-3591     ISO Abbreviation:  Zhonghua Nan Ke Xue     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101093592     Medline TA:  Zhonghua Nan Ke Xue     Country:  China    
Other Details:
Languages:  chi     Pagination:  1045-9     Citation Subset:  IM    
Affiliation:
Department of Andrology, Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China. yzhjiao@126.com
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