| Effects on visual recognition of combined and separate ablations of the entorhinal and perirhinal cortex in rhesus monkeys. | |
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MedLine Citation:
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PMID: 8254384 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Performance on visual delayed nonmatching-to-sample was assessed in rhesus monkeys with combined and separate ablations of the perirhinal and entorhinal cortex, as well as in unoperated controls. Combined (i.e., rhinal cortex) lesions yielded a striking impairment on this task, one almost as severe as that seen after combined amygdalohippocampal removals that included some of this subjacent cortex (Mishkin, 1978; Murray and Mishkin, 1984). Ablations of the perirhinal cortex alone produced a deficit nearly as severe as that found after rhinal cortex lesions, whereas ablations of the entorhinal cortex alone produced only a mild deficit. Contrary to the conclusion from an earlier study (Murray and Mishkin, 1986), the present results demonstrate not only that damage limited to the rhinal cortex is sufficient to produce a severe loss in visual recognition, but also that such damage leads to a far greater loss than damage to any other single structure in the medial part of the temporal lobe. |
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Authors:
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M Meunier; J Bachevalier; M Mishkin; E A Murray |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of neuroscience : the official journal of the Society for Neuroscience Volume: 13 ISSN: 0270-6474 ISO Abbreviation: J. Neurosci. Publication Date: 1993 Dec |
Date Detail:
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Created Date: 1994-01-12 Completed Date: 1994-01-12 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8102140 Medline TA: J Neurosci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 5418-32 Citation Subset: IM |
Affiliation:
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Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, Maryland 20892. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cerebral Cortex / anatomy & histology, physiology* Female Macaca mulatta Male Memory Disorders / physiopathology Vision, Ocular / physiology* Visual Perception / physiology |
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