| Effects of various secretagogues and human carcinoid serum on lymph flow in the cat ileum. | |
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MedLine Citation:
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PMID: 7106519 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previous studies from our laboratory indicate that the lymph flow response of the cat ileum to net volume secretion is dependent upon the mechanism involved in the secretory process, i.e, active secretion (cholera toxin) decreases lymph flow while passive fluid secretion (increased portal pressure, plasma dilution) is associated with a rise in lymph flow. In the present study, we examined the effects of ricinoleic acid, vasoactive intestinal polypeptide, theophylline, histamine, and human carcinoid serum on lymph flow in autoperfused segments of cat ileum. Local intraarterial infusion of theophylline, vasoactive intestinal polypeptide, or human carcinoid serum caused lymph flow to decrease. However, intraluminal placement of ricinoleic acid or intraarterial infusion of histamine produced significant increases in lymph flow. The results indicate that the fluid secretion associated with vasoactive intestinal polypeptide, theophylline, and carcinoid serum are consistent with an active process while ricinoleic acid and histamine secretions are associated with a passive component. |
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Authors:
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D N Granger; R Cross; J A Barrowman |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Gastroenterology Volume: 83 ISSN: 0016-5085 ISO Abbreviation: Gastroenterology Publication Date: 1982 Oct |
Date Detail:
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Created Date: 1982-10-21 Completed Date: 1982-10-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0374630 Medline TA: Gastroenterology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 896-901 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Proteins / analysis Carcinoid Tumor / blood* Cats Histamine / pharmacology Ileum / physiology* Intestinal Secretions / analysis, secretion* Lymph / physiology* Ricinoleic Acids / pharmacology Secretory Rate / drug effects Theophylline / pharmacology Vasoactive Intestinal Peptide / pharmacology |
| Grant Support | |
ID/Acronym/Agency:
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26441//PHS HHS; NHLBI 00816/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Blood Proteins; 0/Ricinoleic Acids; 37221-79-7/Vasoactive Intestinal Peptide; 51-45-6/Histamine; 58-55-9/Theophylline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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