Document Detail


Effects of tuna fish oil on hyperlipidemia and proteinuria in childhood nephrotic syndrome.
MedLine Citation:
PMID:  10730531     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is a randomized, double-blind, placebo-controlled, cross-over study to determine whether tuna fish oil decreased hyperlipidemia and proteinuria in children with steroid-resistant nephrotic syndrome. Five boys were supplemented with both 4 grams of tuna fish oil and placebo in a randomized order for 8 weeks of each treatment separated by 6-week washout period. The results showed no statistically significant difference in serum creatinine, triglyceride, cholesterol, urine protein and creatinine clearance between fish oil supplemented group and placebo group. Small sample size, low dosage, short duration of supplementation and wash-out period are among the important limitations in this study. Further study should be performed to identify the effects of fish oil on this entity in nephrotic syndrome.
Authors:
N Chongviriyaphan; C Tapaneya-Olarn; U Suthutvoravut; S Karnchanachumpol; V Chantraruksa
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  82 Suppl 1     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-04-05     Completed Date:  2000-04-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  S122-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Animals
Child
Cross-Over Studies
Double-Blind Method
Fish Oils*
Humans
Hyperlipidemias / therapy*
Male
Nephrotic Syndrome / therapy*
Proteinuria / therapy*
Treatment Failure
Tuna
Chemical
Reg. No./Substance:
0/Fish Oils

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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