| Effects of the trichothecene mycotoxin diacetoxyscirpenol on feed consumption, body weight, and oral lesions of broiler breeders. | |
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MedLine Citation:
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PMID: 10875768 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three experiments were conducted to determine the effects of 4,15-diacetoxyscirpenol (DAS) on BW, feed consumption, and oral lesions of broiler breeders. In Experiment 1, caged broiler breeder hens were fed 0, 5, 10, or 20 mg DAS/kg diet from 24 to 25 wk of age. There were dose-related decreases in BW and feed consumption indicating feed refusal, as well as dose-related increases in the extent of mouth lesions. The areas of the mouth most sensitive to DAS were associated with the salivary glands and the tip of the tongue. In Experiment 2, individually caged male and female broiler breeders were fed a basal diet containing 0, 5, 10, or 20 mg DAS/kg from 25 to 27 wk of age. There were dose-related decreases in BW and feed consumption for the female broiler breeders, whereas there was a decrease in feed consumption for the male broiler breeders at the 10 and 20 mg DAS/kg levels. In Experiment 3, male broiler breeders were fed 0 or 10 mg DAS/kg diet from 23 to 25 wk of age on a litter floor. For this experiment the daily intake of feed was restricted, and the feed consumption rate was measured. There was an increased amount of unconsumed feed at 23 wk of age due to the presence of DAS. In summary, the experiments provided evidence that DAS caused decreased BW and feed consumption as well as cytotoxic injury including oral lesions in broiler breeders. |
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Authors:
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J Brake; P B Hamilton; R S Kittrell |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Poultry science Volume: 79 ISSN: 0032-5791 ISO Abbreviation: Poult. Sci. Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-10-03 Completed Date: 2000-10-03 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0401150 Medline TA: Poult Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 856-63 Citation Subset: IM |
Affiliation:
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Department of Poultry Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh 27695-7608, USA. jbrake@ncsu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Weight / drug effects* Chickens / physiology* Eating / drug effects* Female Male Mouth Diseases / chemically induced* Mycotoxins / adverse effects Trichothecenes / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Mycotoxins; 0/Trichothecenes; 2270-40-8/diacetoxyscirpenol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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