Document Detail

Effects of treadmill running on the properties of guinea-pig myosin.
MedLine Citation:
PMID:  6325714     Owner:  NLM     Status:  MEDLINE    
The effects of running training on the structure and function of ventricular myosin of guinea-pigs were studied. No differences in body or heart weights could be detected but the heart-to-body weight relation increased significantly (P less than 0.05) in the trained group. Ca2+ activated and K+ activated ventricular myosin ATPase activities as well as the electrophoretic appearances (SDS-PAGE, pyrophosphate-PAGE) did not change after training. Guinea-pig ventricular myosin in nondissociating conditions showed one band migrating close to rat-V3 isomyosin. The myosins of the trained and untrained animals also showed no immunological difference as determined by the competitive ELISA-test: they both shared antigenic determinants common to rat-V1 isomyosin.
I Morano; H Weicker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of molecular and cellular cardiology     Volume:  16     ISSN:  0022-2828     ISO Abbreviation:  J. Mol. Cell. Cardiol.     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-06-21     Completed Date:  1984-06-21     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0262322     Medline TA:  J Mol Cell Cardiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  195-201     Citation Subset:  IM    
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MeSH Terms
Adenosine Triphosphatases / metabolism
Calcium / metabolism
Electron Transport Complex IV / metabolism
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Guinea Pigs
Heart Ventricles / enzymology
Myocardium / enzymology*
Myosins / metabolism*
Physical Exertion*
Potassium / metabolism
Reg. No./Substance:
7440-09-7/Potassium; 7440-70-2/Calcium; EC Transport Complex IV; EC 3.6.1.-/Adenosine Triphosphatases; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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