Document Detail

Effects of topical vehicles on growth of the lipophilic Malassezia species.
MedLine Citation:
PMID:  12234705     Owner:  NLM     Status:  MEDLINE    
In the present study, the abilities of major Malassezia species, M. sympodialis, M. globosa and M. furfur, to assimilate topical agents, which have been widely used as a material of ointment for skin diseases, were tested. Obvious growth of M. furfur on GYEP agar plate was noted in the presence of white petrolatum, purified white petrolatum, hydrophilic ointment and heparinoid in hydrophilic ointment, and also M. sympodialis showed similar growth when they were cultured with hydrophilic or heparinoid in hydrophilic ointment. In contrast, M. globosa did not grow on GYEP in the presence of the any topical agents tested. These results suggest that Malassezia species, especially M. furfur and M. sympodialis, assimilate several topical agents and showed the drug-depended cell growth.
Tomoki Koyama; Toshio Kanbe; Akihiko Kikuchi; Yasushi Tomita
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of dermatological science     Volume:  29     ISSN:  0923-1811     ISO Abbreviation:  J. Dermatol. Sci.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-17     Completed Date:  2002-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9011485     Medline TA:  J Dermatol Sci     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  166-70     Citation Subset:  IM    
Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya 466-8550, Japan.
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MeSH Terms
Administration, Topical
Colony Count, Microbial
Fats / pharmacology*
Malassezia / drug effects*,  genetics,  growth & development*,  physiology
Species Specificity
Vehicles / administration & dosage*,  pharmacology
Reg. No./Substance:
0/Fats; 0/Ointments; 0/Vehicles

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