| Effects of topical 10% ascorbate solution on established corneal ulcers after severe alkali burns. | |
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MedLine Citation:
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PMID: 7061209 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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When established corneal ulcers induced by alkali burning were treated with 10% ascorbate drops, no perforation occurred, in contrast to a 25% incidence in the control group. If perforations and descemetoceles were grouped together, these difference became insignificant (i.e., 14.2% ascorbate-treated vs. 25% control). Prolongation of descemetocele presence without perforation in the ascorbate-treated group indicated some therapeutic effect. We conclude that topical ascorbate does not substantially alter the outcome of established corneal ulcers. |
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Authors:
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R R Pfister; C A Paterson; S A Hayes |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Investigative ophthalmology & visual science Volume: 22 ISSN: 0146-0404 ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Publication Date: 1982 Mar |
Date Detail:
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Created Date: 1982-05-21 Completed Date: 1982-05-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 382-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Alkalies / adverse effects Animals Ascorbic Acid / therapeutic use* Burns, Chemical / complications* Corneal Ulcer / drug therapy*, etiology Eye Burns / complications* Rabbits |
| Grant Support | |
ID/Acronym/Agency:
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EY 02018/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Alkalies; 50-81-7/Ascorbic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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