Document Detail

Effects of titanium mesh implant on dosimetry during Gamma Knife radiosurgery.
MedLine Citation:
PMID:  22955648     Owner:  NLM     Status:  In-Data-Review    
Calvarial reconstruction following resection of tumors involving the skull is often followed by stereotactic radiosurgery. Prior studies have addressed the effects of various cranioplasty materials on dose distributions in linac-based radiosurgery. We aim to determine the effects of titanium mesh implants on Gamma Knife dose. Radiation backscatter and transmission were measured for eight types of titanium mesh using film, ion chamber, and Theratron Co-60 teletherapy device. A single mesh was selected for Gamma Knife irradiation using a CaSO4 skull filled with ballistics gel. Dose profiles for reconstructed and intact skulls were compared with the planning system prediction at 2.5 and 5.5 cm depth. Titanium contact backscatter and transmission dose perturbations ranged from -18% to 23%. Radiation dose measured at 1.5 cm below the calvarial implant increased by 0.5% to 3.3% relative to bone. Measured Gamma Knife dose profile diameters agreed with expected profiles. Maximum dose within the intact phantom was 3% less than planned due to skull attenuation. Maximum dose within the reconstructed phantom was between the intact phantom and planned doses. Titanium mesh implants and hydroxyapatite cranioplasty result in minimal alteration (< 3%) in the delivered Gamma Knife dose.
Joseph T Rakowski; Karen Chin; Sandeep Mittal
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Publication Detail:
Type:  Journal Article     Date:  2012-09-06
Journal Detail:
Title:  Journal of applied clinical medical physics / American College of Medical Physics     Volume:  13     ISSN:  1526-9914     ISO Abbreviation:  J Appl Clin Med Phys     Publication Date:  2012  
Date Detail:
Created Date:  2012-09-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101089176     Medline TA:  J Appl Clin Med Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3833     Citation Subset:  IM    
Karmanos Cancer Center.
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