| Effects of tilt and exercise on signal-averaged electrocardiogram after acute myocardial infarction. | |
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MedLine Citation:
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PMID: 2354703 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine whether enhanced sympathetic activity could alter a non-invasive index of cardiac instability, we analysed the effects of 90 degrees head-up tilt and submaximal exercise stress test on high amplification signal-averaged electrocardiogram in 64 patients after acute myocardial infarction. At rest, ventricular late potentials were detected in 25% of patients, characterized by a significant prolongation of filtered QRS complex (137 +/- 3 vs 115 +/- 2 ms) and of its components smaller than 40 microV (38 +/- 2 vs 16 +/- 1 ms), as well as by a reduced root mean square voltage calculated for the terminal 40 ms of QRS complex (RMS40 voltage) (19 +/- 1 vs 75 +/- 9 microV) in comparison to patients without micropotentials. Sympathetic activation induced by tilt caused a significant increase in heart rate (from 67 +/- 3 to 79 +/- 3 beats min-1) but did not modify either the incidence of ventricular late potentials or the values of any of the signal-averaged electrocardiogram parameters considered. In 19 patients, recordings were also obtained during a submaximal bicycle exercise stress test at a heart rate of 114 +/- 4 beats min-1 and with systolic arterial blood pressure at 153 +/- 6 mmHg. No effect on signal-averaged electrocardiogram parameters was detectable during this experimental intervention. These data indicate that after myocardial infarction, sympathetic activation does not seem to modify signal-averaged electrocardiogram parameters. |
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Authors:
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F Lombardi; M L Finocchiaro; L Dalla Vecchia; R Sala; M Garimoldi; G Baselli; S Cerutti; A Malliani |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: European heart journal Volume: 11 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1990 May |
Date Detail:
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Created Date: 1990-07-20 Completed Date: 1990-07-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 421-8 Citation Subset: IM; S |
Affiliation:
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Patologia Medica, Centro Fidia, Cardiologia, Ospedale L. Sacco, Milano, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Electrocardiography* Exercise / physiology* Female Heart Conduction System / physiopathology Humans Male Middle Aged Myocardial Infarction / diagnosis*, physiopathology Posture / physiology* Signal Processing, Computer-Assisted* Sympathetic Nervous System / physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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