| Effects of thymosin alpha-1 on erythrocyte lipid levels and erythrocyte membrane (Na(+)-K+)-ATPase activity in experimental hypercholesterolemia. | |
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MedLine Citation:
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PMID: 9559439 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thymosin alpha-1 is an active polypeptide isolated from thymus. This polypeptide is widely used in the diagnosis and treatment of many diseases, especially immune diseases. In this present study, we examined the effects of thymosin alpha-1 on plasma and erythrocyte lipid levels and the changes in erythrocyte membrane (Na+, K+)ATPase activity in hypercholesterolemic rabbits. The erythrocyte lipid levels decreased, whereas the erythrocyte membrane (Na+, K+)ATPase activity increased significantly in these rabbits after thymosin alpha-1 injection. These findings suggest that thymosin alpha-1 is effective on both the lipid level and erythrocyte membrane (Na+, K+)ATPase activity. |
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Authors:
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C Gökkuşu; E Ademoğlu; H Oz; U M Türkoğlu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Japanese journal of medical science & biology Volume: 50 ISSN: 0021-5112 ISO Abbreviation: Jpn. J. Med. Sci. Biol. Publication Date: 1997 Apr |
Date Detail:
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Created Date: 1998-05-29 Completed Date: 1998-05-29 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0243706 Medline TA: Jpn J Med Sci Biol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 45-53 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, Faculty of Medicine, University of Istanbul, Capa, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Erythrocyte Membrane / enzymology* Hypercholesterolemia / blood* Lipids / blood* Rabbits Sodium-Potassium-Exchanging ATPase / blood* Thymosin / analogs & derivatives*, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Lipids; 0/thymalfasin; 61512-21-8/Thymosin; EC 3.6.3.9/Sodium-Potassium-Exchanging ATPase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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