| Effects of thrombolysis in the evolution of right bundle-branch block complicating an acute anterior myocardial infarction. | |
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MedLine Citation:
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PMID: 11712825 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: There is scant information about the effects of thrombolysis in the evolution of right bundle-branch block (RBBB) in the setting of acute anterior myocardial infarction. The aim of this study has been to analyse these effects and its impact on prognosis. METHODS: We studied 54 patients who presented a RBBB related to an acute anterior myocardial infarction. We defined two groups: those who received thrombolytic treatment and those who did not. We analysed the evolution of RBBB (transience, moment of onset, moment of disappearance) and its relationship with in-hospital mortality.Twenty-one patients (39%) received thrombolytic treatment (groupT) and 33 patients (61%) (group NT) did not. RESULTS: The incidence of late appearance (> 6 h) of RBBB was less frequent in group T compared with group NT (10% vs. 33%, p = 0.04). The incidence of transient block was similar in the two groups (57% vs. 45%, p ns). However, early disappearance of RBBB (in < 6 hours) was more common in group T than in group NT (33% vs. 9%, p = 0.04). Mortality was higher in patients with RBBB present at 24 h after admission) than in those with RBBB resolved in less than 24 hours (in group NT, 55% vs. 8%, p = 0.02 and in group T 50% vs. 0%, p = 0.02, respectively). CONCLUSIONS: Thrombolysis seems to influence the moment of onset and disappearance of RBBB by promoting its early disappearance and avoiding its late appearance. Disappearance of RBBB is associated with a better prognosis. |
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Authors:
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J M Alegret; V Martí; E Rodriguez-Font; C Alonso; J Guindo; J M Domínguez De Rozas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta cardiologica Volume: 56 ISSN: 0001-5385 ISO Abbreviation: Acta Cardiol Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-11-19 Completed Date: 2002-03-01 Revised Date: 2009-11-03 |
Medline Journal Info:
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Nlm Unique ID: 0370570 Medline TA: Acta Cardiol Country: Belgium |
Other Details:
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Languages: eng Pagination: 297-301 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. txalegret@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anticoagulants / therapeutic use* Bundle-Branch Block / etiology*, mortality Female Heparin / therapeutic use* Humans Male Middle Aged Myocardial Infarction / complications*, drug therapy*, mortality Prognosis Risk Factors Streptokinase / therapeutic use* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 9005-49-6/Heparin; EC 3.4.-/Streptokinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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