Document Detail


Effects of terbutaline on the pressure volume relationship in fetal rabbit lung.
MedLine Citation:
PMID:  211788     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pressure-volume relationship in preterm rabbit lung was studied at 28 days of gestation. Injection of 0.1 mg terbutaline, a selective beta2-receptor stimulating drug, significantly increased the volume of air at equivalent low transpulmonary pressures, compared to a saline treated group and an untreated group. These findings indicate an increased pulmonary distensibility of the fetal rabbit lung after terbutaline administration. The mechanism of action is discussed and surfactant mediated effects are suggested to be the probable explanation.
Authors:
B Bergman; T Hedner; P Lundborg
Related Documents :
576498 - Restoration of lung pressure-volume characteristics with surfactant: comparison of nebu...
8472578 - Exogenous surfactant therapy increases static lung compliance, and cannot be assessed b...
11704608 - Polyethylene glycol/surfactant mixtures improve lung function after hcl and endotoxin l...
12904188 - A lung recruitment maneuver immediately before rescue surfactant therapy does not affec...
10583358 - Management of peri-operative pulmonary hypertension in a patient presenting for a porto...
24087988 - Kinetic study of the oh + glyoxal reaction: experimental evidence and quantification of...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  57     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1978  
Date Detail:
Created Date:  1978-11-18     Completed Date:  1978-11-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  323-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Female
Lung / drug effects,  embryology*
Lung Volume Measurements
Pregnancy
Pressure
Pulmonary Surfactants
Rabbits
Receptors, Adrenergic, beta / drug effects
Sodium Chloride / pharmacology
Terbutaline / pharmacology*
Chemical
Reg. No./Substance:
0/Pulmonary Surfactants; 0/Receptors, Adrenergic, beta; 23031-25-6/Terbutaline; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Ultrastructural localization of rabies virus antigens in infected trigeminal ganglion of hamsters.
Next Document:  Ultrasonography and computer tomography in orbital diagnosis. With special reference to dysthyroid o...