| Effects of temporary clipping during aneurysm surgery. | |
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MedLine Citation:
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PMID: 18953746 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Intraoperative aneurysm rupture is associated with a high morbidity and mortality. Temporary vessel occlusion is an integral part of aneurysm clipping to avoid intraoperative hemorrhage. The information concerning the role of temporary occlusion regarding the development of cerebral vasospasm is sparse. The aim of this study was to provide more information in this field. METHODS: We operated on 292 patients suffering from cerebral aneurysms. The data were reviewed from a prospectively collected databank, which includes information about the severity of subarachnoid hemorrhage, as well as transcranial Doppler data and surgical data such as temporary occlusion. RESULTS: In 50% of our patients, temporary occlusion was performed during surgery. Twenty-nine percent showed an ischemic lesion in the CCT post-operatively, and in 58% of these patients, temporary occlusion was performed (versus 47% without temporary occlusion, p = 0.09). The mean occlusion time was longer in patients with radiologic signs of infarction. Furthermore, patients having unfavorable outcome showed a longer temporary occlusion time. Thirty-four percent of patients who underwent temporary vessel occlusion developed vasospasm postoperatively (versus 20% without temporary occlusion, p < 0.006). Temporary occlusion time correlated to the development of vasospasm as defined by transcranial Doppler flow velocity. Forty-eight percent of the patients treated using temporary occlusion suffered from middle cerebral artery aneurysm (versus 22% without temporary occlusion, p < 0.0001). An increased blood flow velocity was mostly seen in this region (p < 0.003). CONCLUSION: According to our results, it seems to be the possible that temporary vessel occlusion is an additional factor in aggravating vasospasm after aneurysmatic subarachnoid hemorrhage. |
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Authors:
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Chris Woertgen; Ralf Dirk Rothoerl; Ruth Albert; Karl-Michael Schebesch; Odo-Winfried Ullrich |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurological research Volume: 30 ISSN: 0161-6412 ISO Abbreviation: Neurol. Res. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-10-27 Completed Date: 2009-02-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905298 Medline TA: Neurol Res Country: England |
Other Details:
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Languages: eng Pagination: 542-6 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, University of Regensburg, Regensburg, Germany. chris.woertgen@klinik.uni-regensburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Analysis of Variance Aneurysm / classification, surgery* Cerebral Angiography / methods Female Humans Male Middle Aged Postoperative Complications* Prospective Studies Retrospective Studies Surgical Instruments / adverse effects* Ultrasonography, Doppler, Transcranial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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