Document Detail

Effects of tachycardia with normal and ectopic ventricular activation on S-T segment potential and patterns in the dog.
MedLine Citation:
PMID:  4031725     Owner:  NLM     Status:  MEDLINE    
Tachycardia induced by atrial pacing in the dog increases the intensity of potentials recorded on the body surface during the ST-T interval. The effects of tachycardia caused by ectopic right or left ventricular stimulation on ventricular recovery potentials were studied in 30 dogs. Rate was increased in a stopwise manner from 90 to 250 beats per minute by atrial pacing (ten dogs), or by left atrial-right ventricular sequential pacing (ten dogs), or by left atrial-left ventricular sequential pacing (ten dogs). ECG effects were determined by construction of body surface isopotential maps from voltages registered from 84 torso electrodes using a P-R segment baseline. Ectopic stimulation intensified the repolarization maximum and shifted its location to correspond with sites of epicardial stimulation. These findings reflect a reduced cancellation of transventricular differences in recovery times, with earliest recovery occurring at earliest activated sites. Increasing rate with any one activation pattern linearly increased potential extrema magnitudes without further changes of spatial features. This singular response to tachycardia regardless of activation sequence is consistent with an increase in the apparent moment of a repolarization dipole without alteration of its orientation.
D M Mirvis; J Marin-Garcia
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  18     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  1985 Jul 
Date Detail:
Created Date:  1985-09-30     Completed Date:  1985-09-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-31     Citation Subset:  IM    
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MeSH Terms
Cardiac Pacing, Artificial
Heart Atria / physiopathology
Heart Conduction System / physiopathology
Heart Rate
Heart Ventricles / physiopathology
Tachycardia / physiopathology*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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