| Effects of synthetic kassinin on splanchnic circulation and exocrine pancreas in dogs. | |
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MedLine Citation:
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PMID: 3244558 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effects of intravenously administered synthetic kassinin on splanchnic circulation and exocrine pancreatic secretion were examined in six anesthetized dogs. Kassinin caused dose-related increases in the blood flow in superior mesenteric artery and portal vein, and produced an initial increase followed by a decrease in pancreatic blood flow, but did not affect the exocrine pancreatic secretion. This study demonstrates that kassinin affects splanchnic blood flow in dogs, and suggests that kassinin or a kassinin-like substance functions as a neuropeptide controlling the splanchnic circulation in mammalian species. |
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Authors:
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R Doi; K Inoue; M Kogire; S Sumi; K Takaori; M Yun; H Yajima; T Tobe |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Peptides Volume: 9 ISSN: 0196-9781 ISO Abbreviation: Peptides Publication Date: 1988 Sep-Oct |
Date Detail:
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Created Date: 1989-05-26 Completed Date: 1989-05-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8008690 Medline TA: Peptides Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1055-8 Citation Subset: IM |
Affiliation:
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First Department of Surgery, Faculty of Medicine, Kyoto University, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dogs Female Kassinin / pharmacology* Male Pancreas / blood supply, drug effects, secretion* Pancreatic Juice / drug effects, secretion* Reference Values Regional Blood Flow / drug effects Secretin / pharmacology Splanchnic Circulation / drug effects* |
| Chemical | |
Reg. No./Substance:
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1393-25-5/Secretin; 63968-82-1/Kassinin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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