Document Detail


Effects of sympathetic and parasympathetic stimulation on the induction of atrial flutter in dogs with aseptic pericarditis.
MedLine Citation:
PMID:  1811089     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To study the effects of sympathetic stimulation (SS) and vagal stimulation (VS) on the induction of atrial flutter (AF) and its cycle length, aseptic pericarditis was produced surgically in 17 adult mongrel dogs. Programmed atrial stimulation was used to induce AF and to determine the effective refractory periods (ERP) and maximum conduction delay (maxCD) of the atrium. These tests were performed before and during stimulation of the right cervical vagus nerve and the right stellate ganglion. Results showed: (1) AF could be induced in animals with short ERP and large maxCD before SS; (2) ERP was significantly shortened, maxCD was significantly increased by VS; (3) During SS, ERP was slightly shortened, but there were no changes in maxCD and the induction rate of AF; (4) The cycle length of AF was shortened by SS, however, the cycle length of AF was shortened more notably by VS than by SS. From these findings, a shortening of the ERP and an increase in maxCD appear to be related to an increased AF induction rate by VS.
Authors:
K Yano; T Hirata; M Hirata; O Hano; Y Matsumoto; T Mitsuoka; K Abe; K Hashiba
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese heart journal     Volume:  32     ISSN:  0021-4868     ISO Abbreviation:  Jpn Heart J     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-06-04     Completed Date:  1992-06-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401175     Medline TA:  Jpn Heart J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  811-25     Citation Subset:  IM    
Affiliation:
Third Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Atrial Flutter / etiology,  physiopathology*
Cardiac Pacing, Artificial
Dogs
Electrocardiography
Pericarditis / complications*
Refractory Period, Electrophysiological
Stellate Ganglion / physiopathology*
Vagus Nerve / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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