| Effects of surgical skin incision on respiration in patients anaesthetized with enflurane. | |
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MedLine Citation:
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PMID: 8679348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We measured ventilation in 12 subjects anaesthetized with enflurane (end-tidal concentration 1.25-1.45%) and nitrous oxide to assess the effect of surgical stimulation on ventilation in humans. Tidal volume and respiratory timing were measured by pneumotachograph before and just after a standardized surgical skin incision. Surgical stimulation increased ventilation by increasing tidal volume, which increased progressively over the first five breaths after incision. The first breath after the stimulus was prolonged, but the timing of the subsequent breaths returned rapidly to the duration observed before incision. Ventilation increased from median 3.6 (quartiles 2.9, 4.3) to 5.4 (3.8, 7.0) litre min-1 (P < 0.01). The increased tidal volume was not associated consistently with shortening of inspiratory duration. |
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Authors:
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R W Sutherland; G B Drummond |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British journal of anaesthesia Volume: 76 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1996-08-21 Completed Date: 1996-08-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 777-9 Citation Subset: IM |
Affiliation:
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Department of Anaesthetics, Royal Infirmary, Edinburgh. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia, Inhalation* Anesthetics, Inhalation* Enflurane* Female Humans Male Middle Aged Respiration* Skin / surgery* Tidal Volume |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Inhalation; 13838-16-9/Enflurane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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