| Effects of surface dehydration on mucosal wave amplitude and frequency in excised canine larynges. | |
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MedLine Citation:
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PMID: 21493398 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Evaluate the effect of vocal fold surface dehydration on mucosal wave amplitude and frequency. STUDY DESIGN: Controlled test-retest. SETTING: Larynges were mounted on an excised larynx phonation system and attached to a pseudolung in a triple-walled sound-attenuated room that eliminated background noise and maintained a stabilized room temperature and humidity level. SUBJECTS AND METHODS: High-speed video was recorded for 8 excised canine larynges during exposure to dehumidified air at 20 cm H(2)O. Control trials consisted of high-speed videos recorded for 2 excised canine larynges during exposure to humidified air at the same pressure. RESULTS: In the majority of larynges, increased levels of dehydration were correlated with decreased amplitude and frequency. The slope of the linear regression fitted to the change in amplitude (P = .003) and the percent change (P < .001) between the initial and final trials were significantly decreased in dehydrated larynges. These measurements with respect to the change in frequency were also significantly decreased in dehydrated larynges (P < .001; P = .027). CONCLUSION: Vocal fold surface dehydration caused a decrease in mucosal wave amplitude and frequency. This study provides objective, quantitative support for the mechanism of voice deterioration observed after extreme surface dehydration. |
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Authors:
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Rachel E Witt; Lindsay N Taylor; Michael F Regner; Jack J Jiang |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: 144 ISSN: 1097-6817 ISO Abbreviation: Otolaryngol Head Neck Surg Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-04-15 Completed Date: 2011-06-28 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: England |
Other Details:
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Languages: eng Pagination: 108-13 Citation Subset: IM |
Affiliation:
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University of Wisconsin-Madison School of Medicine and Public Health, Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, Madison, WI 53706, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dehydration Dogs Laryngeal Mucosa / physiology* Laryngectomy* Larynx / cytology*, surgery Mucous Membrane / cytology Phonation / physiology* Vocal Cords / physiology* |
| Grant Support | |
ID/Acronym/Agency:
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R01 DC005522-01/DC/NIDCD NIH HHS; R01 DC008850 AND R01 DC005522/DC/NIDCD NIH HHS; R01 DC008850-01/DC/NIDCD NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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