Document Detail

Effects of supervised treadmill walking training on calf muscle capillarization in patients with intermittent claudication.
MedLine Citation:
PMID:  18505746     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to evaluate the effects of supervised treadmill walking training on the calf muscle capillarization in patients with intermittent claudication. The first 12-week period was a non-exercise, within-subject control stage, and the second 12-week period was an exercise training stage. Calf muscle biopsy and functional capacity measurement were performed at baseline, preexercise and postexercise training. In all, 11 subjects completed all procedures. Their average age was (mean +/- standard deviation) 73.9 +/- 5.5 years and resting ankle-to-brachial systolic blood pressure index was 0.57 +/- 0.11. After exercise training, the difference between the pretraining and posttraining capillaries in contact with type IIx and IIa muscle fibers for each subject was significantly correlated with an improved pain-free walking time, r = 0.69 and r = 0.62 (both P < .05), respectively. This finding suggests that the change in calf muscle capillarization might contribute to the improved walking capacity following supervised treadmill walking training in patients with intermittent claudication.
Jianxiong Wang; Shi Zhou; Roger Bronks; John Graham; Stephen Myers
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2008-05-27
Journal Detail:
Title:  Angiology     Volume:  60     ISSN:  1940-1574     ISO Abbreviation:  Angiology     Publication Date:    2009 Feb-Mar
Date Detail:
Created Date:  2009-02-04     Completed Date:  2009-02-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  36-41     Citation Subset:  IM    
Department of Exercise Science and Sport Management, Southern Cross University, Lismore, Australia.
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MeSH Terms
Capillaries / physiopathology
Combined Modality Therapy
Double-Blind Method
Exercise Therapy*
Ginkgo biloba
Intermittent Claudication / drug therapy,  physiopathology,  therapy*
Muscle, Skeletal / blood supply*
Neovascularization, Physiologic*
Plant Preparations / therapeutic use
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Plant Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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