Document Detail

Effects of supervised exercise on lipid profiles and blood pressure control in people with type 2 diabetes mellitus: A meta-analysis of randomized controlled trials.
MedLine Citation:
PMID:  23116535     Owner:  NLM     Status:  Publisher    
AIMS: Our study's purpose was to perform a systematic review to assess the effect of supervised exercise interventions on lipid profiles and blood pressure control. METHODS: We searched electronic databases and selected studies that evaluated the effect of supervised exercise intervention on cardiovascular risk factors in adult people with type 2 diabetes. We used random effect models to derive weighted mean differences of exercise on lipid profiles and blood pressure control. RESULTS: Forty-two RCTs (2808 subjects) met inclusion criteria and are included in our meta-analysis. Structured exercise was associated with a change in systolic blood pressure (SBP) of -2.42mmHg (95% CI, -4.39 to -0.45mmHg), diastolic blood pressure (DBP) of -2.23mmHg (95% CI, -3.21 to -1.25mmHg), high-density lipoprotein cholesterol (HDL-C) of 0.04mmol/L (95% CI, 0.02-0.07mmol/L), and low-density lipoprotein cholesterol (LDL-C) of -0.16mmol/L (95% CI, -0.30 to -0.01mmol/L). Heterogeneity was partially explained by age, dietary co-intervention and the duration and intensity of the exercise. CONCLUSIONS: Supervised exercise is effective in improving blood pressure control, lowering LDL-C, and elevating HDL-C levels in people with diabetes. Physicians should recommend exercise for their adult patients with diabetes who can safely do so.
Yasuaki Hayashino; Jeffrey L Jackson; Norio Fukumori; Fumiaki Nakamura; Shunichi Fukuhara
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-29
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  -     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-11-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Department of Healthcare Epidemiology, Kyoto University Graduate School of Medicine and Public Health, Kyoto 606-8501, Japan; Department of Endocrinology, Tenri Hospital, Nara, Japan. Electronic address:
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