| Effects of substituted 1,2,3-triazoles on adenosine deaminase, guanine deaminase and xanthine oxidase. | |
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MedLine Citation:
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PMID: 583599 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The action of some known and new synthesized substituted 1,2,3-triazoles on adenosine deaminase, guanine deaminase and xanthine oxidase was studied. The effect of substituents in 1, 4 and 5 positions was studied and discussed. The presence of a carboxamido group in 4 position seems to be essential in the binding to adenosine deaminase. |
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Authors:
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A Lucacchini; D Segnini; A Da Settimo; O Livi |
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Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: The Italian journal of biochemistry Volume: 28 ISSN: 0021-2938 ISO Abbreviation: Ital. J. Biochem. Publication Date: 1979 May-Jun |
Date Detail:
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Created Date: 1981-03-24 Completed Date: 1981-03-24 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376564 Medline TA: Ital J Biochem Country: ITALY |
Other Details:
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Languages: eng Pagination: 194-206 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Deaminase
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antagonists & inhibitors* Aminohydrolases / antagonists & inhibitors* Animals Binding Sites Cattle Guanine Deaminase / antagonists & inhibitors* Nucleoside Deaminases / antagonists & inhibitors* Rabbits Structure-Activity Relationship Triazoles / chemical synthesis, pharmacology* Xanthine Oxidase / antagonists & inhibitors* |
| Chemical | |
Reg. No./Substance:
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0/Triazoles; EC 1.17.3.2/Xanthine Oxidase; EC 3.5.4.-/Aminohydrolases; EC 3.5.4.-/Nucleoside Deaminases; EC 3.5.4.3/Guanine Deaminase; EC 3.5.4.4/Adenosine Deaminase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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