Document Detail

Effects of stress on muscarinic mechanisms.
MedLine Citation:
PMID:  3287239     Owner:  NLM     Status:  MEDLINE    
Hyperactivity of muscarinic mechanisms may be involved in the patho-physiology of depressive disorders and stress. The literature emphasizes the impact of stress on aminergic networks and muscarinic mechanisms are generally not accorded a significant role in the neurobiology of stress. However, experiments in man and animals indicate that acute and chronic stress activate central muscarinic mechanisms. The literature reporting these results is reviewed.
S C Dilsaver
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Neuroscience and biobehavioral reviews     Volume:  12     ISSN:  0149-7634     ISO Abbreviation:  Neurosci Biobehav Rev     Publication Date:  1988  
Date Detail:
Created Date:  1988-07-01     Completed Date:  1988-07-01     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7806090     Medline TA:  Neurosci Biobehav Rev     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  23-8     Citation Subset:  IM    
Department of Psychiatry, Ohio State University, Columbus 43210-1228.
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MeSH Terms
Depression / physiopathology*
Receptors, Muscarinic / physiology*
Stress, Psychological / physiopathology*
Grant Support
Reg. No./Substance:
0/Receptors, Muscarinic

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